Home About Articles UC Irvine School of Medicine researchers identify link between colon cancer and metabolism

UC Irvine School of Medicine researchers identify link between colon cancer and metabolism

More than 60 years ago Otto Warburg recognized that cancer cells differ from normal cells in the metabolic pathway they use for the oxidation of sugar. Rather than the typical series of oxidative steps that take place in the citric acid cycle, cancer cells metabolize sugar via the glycolytic pathway irrespective of whether oxygen is present or not. In The EMBO Journal, researchers in the United States report that the reason for this difference in colon cancer is changes in the Wnt signaling pathway, an essential communication pathway operating in these tumours.

Read more about Professor Marian Waterman’s research here.