Chin-Rang Yang, a recent postdoctoral alumnus of the Biomedical Informatics Training (BIT) Program administered by the UCI Institute for Genomics and Bioinformatics (IGB), has accepted an appointment as an Assistant Professor in the Department of Oncology of the Simmons Comprehensive Cancer Center at the University of Texas Southwestern Medical Center at Dallas. He will also be awarded a joint appointment in the Department of Bioengineering at the University of Texas at Dallas and serve as a systems biology liaison between the medical school and the UT Dallas campus.
“My academic background is a good fit with Southwestern’s needs,” said Yang. He holds a B.S. in Medical Technology (National Taiwan U.), an M.S. in Information Technology (Rochester Institute of Technology), and a Ph.D. in Developmental Biology and Human Oncology (U. Wisconsin-Madison).
For the past three years, Yang has been working with IGB faculty advisors Mjolsness (Bren School of Information and Computer Sciences) and Hatfield (School of Medicine) on the Systems Biology of Metabolic Networks project. Applying his biology expertise and computational biology skills, Yang has developed computational methods that facilitate computational modeling of the mechanistic details of complex biological systems and networks. Hatfield explains, “Dr. Yang’s computational methods incorporate the details of metabolic and genetic mechanisms that accurately simulate and predict cellular regulatory patterns and networks at levels of accuracy not possible by currently employed methods”. Unlike these other simplified models, Yang’s new systems biology approaches hold real promise for accurate computer simulations of normal and malignant life processes.
In his new faculty position at Southwestern Medical Center, Yang will apply the computational systems biology methods he has developed in the IGB at UCI to predict the effects of drug interventions on the cancer process. He also will help develop a graduate education program in Bioinformatics.