Chris has developed 'Scanfold', which forms the distributed computational infrastructure used within DNA nanotechnology projects at UCI. Scanfold distributes melting temperature & DNA secondary structure calculation jobs among several compute nodes in a parallel fashion. Scanfold has been successfully used with well over 100 compute nodes to deliver results within days that otherwise would have taken months on a single machine. We have successfully applied this technology as a subroutine in an optimization algorithm written by Dr. Richard Lathrop for synthetic gene construction projects, the results of which have succesfully gone from in silico to in vitro via collaboration with both Dr. Wesley Hatfield and Dr. Luis Villarreal. Most recently, Scanfold is being employed in a project with Dr. Gregory Weiss to improve and understand the efficency of shotgun kunkel mutagenesis experiments. Scanfold is also currently being employed in a promising DNA nanotechnology experiment to precisely construct DNA nanostructures. This work is also a collaboration with Dr. Wesley Hatfield. More information at: http://www.ics.uci.edu/~cwassman
