The Institute for Genomics and Bioinformatics provides a number of services for academics, companies, and others in life sciences research and development. These include a variety of software programs, Web servers, and databases in chemoinformatics, bioinformatics, computational biology, and systems biology.

Examples of specific areas of research include: sequence analysis, protein structure and function prediction; molecular simulations and docking; computational drug screening and design; comparative genomics; regulatory genomics; analysis of high-throughput data, such as DNA microarray data and high sequnecing throughput data; mathematical modeling of biological systems. Research methods encompass computational, statistical, and machine-learning approaches.

The UCI DNA & Protein MicroArray Facility is available to UCI investigators and life science companies for gene expression profiling and other projects. Cyber-T, a freely available online program of the IGB, has been ranked by investigators from Harvard University and the Pasteur Institute as the best commercial or public software package for the analysis and interpretation of DNA microarray data [Choe, SE et al. (2005) Genome Biol. 6(2):R16.]. For more information, please contact Denis Heck.

CODA Genomics, Inc., a synthetic biology company in Irvine CA, has obtained licenses from the University for the commercialization of pioneering DNA assembly and protein expression technologies developed in the IGB. Other IGB/UCI life science technologies are available to be licensed for industry applications. For information, please contact Pierre Baldi.