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Technology Transfer

IGB strives to transfer the technology developed in its laboratories into commercial applications and operates as an incubator. IGB fostered the faculty founding of several startup companies. The success rate of these startup companies is well above the national average. These include:

  • Antigen Discovery Inc. (Irvine, CA) [faculty founder: P. Felgner]. Antigen discovery is a proteome-on-a chip company for antigen discovery and other immunological applications. IGB faculty were instrumental in helping the company develop its protein chip technology as well as the computational technologies required for analyzing the complex signals produced by these chips.

  • Verdezyne, Inc. (Carslbad, CA) [faculty founders: G.W. Hatfield, R Lathrop]. Verdezyne is an industrial biotechnology company that is leveraging technologies developed at UCI to produce industrial chemicals from renewable non-food sources. They have developed technologies and are commercializing processes that create a positive impact on the environment by replacing important petrochemicals with chemicals produced by microorganisms from sustainable feedstocks, at a lower cost. Verdezyne currently employs more than 100 employees including several UCI graduates.

  • Reaction Explorer, LLC (Irvine, CA) [faculty founders: P. Baldi and former MD/PhD Student J Chen]. Reaction Explorer has developed an expert system for organic reactions in chemistry which is used to power an interactive education system for college-level organic chemistry. Wiley has acquired an exclusive license to the system and is distributing it worldwide.

  • Actavalon Inc. (Corona del Mar, CA) [faculty founders: R Amaro, G. W. Hatfield, P Kaiser, R. Lathrop, S. Rychnovsky]. Actavalon is a pharmaceutical company employing proprietary computational, biological, and chemical methods to develop small molecule drugs for treatment of a broad spectrum of human cancers.

  • 4Design Biosciences LLC (Corona del Mar) [faculty founders: S George, G.W. Hatfield, C.C. Hughes, A. Lee]. 4D scientists have pioneered the development of high-throughput microfluidic devices for multiple physiologically-relevant 3D human micro-organ systems that receive their oxygen, nutrients, and drugs through living blood vessels, just as tissues do in the body.

In addition to providing high paying jobs for UC graduates and supporting the California economy, the UC Regents have obtained an equity position in two of the IGB spin off companies, Verdezyne Inc. and Actavalon, Inc., and have regularly received royalties from Reaction Explorer, LLC. Other companies license IGB's software. For instance, Schrodinger has licensed IGB's protein structure prediction software.